生物化学510章练习题英文版.docx

生物化学510章练习题英文版.docx

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生物化学510章练习题英文版

ExercisesofChapter5-10

A

1.Whichcantransportacyl-CoAintotheMitochondria?

（）

A.apolipoproteinB.lipoproteinC.albuminD.citrateE.carnitine

2.Inwhichfollowingconditionsareketonebodiessynthesisgreatlyaccelerated?

（）

A.glycolysisisenhancedB.fatmobilizationisenhancedC.fattyacidsynthesisisenhanced

D.malonylCoAisreducedE.aerobicoxidationofglucoseisenhanced

3.HowmanymolesofATPareyieldedwhen1molglycerolisoxidizedtoCO2andH2O?

（）

A.19B.16.5/18.5C.20/22D.23E.17

4.whichisthekeyenzymeintheregulationofFAsynthesis?

（）

A.fattyacidsynthaseB.acetyl-CoAcarboxylaseC.keto-acyl-ACPsynthase

D.enoyl-ACPreductaseE.thioesterase

5.NADPHinFAsynthesiscomesfrom（）:

A.aerobicoxidationofglucoseB.glycolyticpathwayC.gluconeogenesis

D.pentosephosphatepathwayE.glucuronatepathway

6.whichisnotconcernedwiththecholesterolbiosynthesis?

A.acetyl-CoAB.HMGCoAC.NADPH+H+D.seualeneE.glycerol

7.theactiveformofcholineinphospholipidbiosynthesisis:

A.ADP-cholineB.UDP-cholineC.CDP-cholineD.GDP-cholineE.CMP-choline

8.whichisnotconcernedwiththeglycerophospholipidbiosynthesis?

A.serineB.GTPC.ATPD.CTPE.choline

9.whichisspecificfunctionofapoAⅠ?

A.activatesLPLB.inhibitsHLC.activatesLCATD.inhibitsLCATE.activatesACAT

10.whichisnotrequiredinβ-OxidationofFattyAcids

A.CoASHB.NADP+C.carnitineD.FADE.NAD+

11.whichistheprimarycarrierofcholesterolinthebloodofhumans?

A.CMB.HDLC.VLDLD.LDLE.IDL

12.HowmanymolesofATPareyieldedwhen1molstearicacid（18C）isoxidizedtoCO2andH2O?

（）

A.146B.120C.165D.182E.199

13.whichisanintermediateonthepathwayforsynthesisofketonebodiesandcholesterol?

A.malonylCoAB.acetoacetyl-CoAC.HMGCoAD.acetyl-CoAE.acetoacetate

14.whichisprostheticgroupofacetyl-CoAcarboxylase?

A.NAD+B.biotinC.NADP+D.FADE.FMN

15.whichisthekeyenzymeintheregulationofcholesterolsynthesis?

（）

A.HMGCoAsynthaseB.squalenemonooxygenaseC.HMGCoAreductase

D.squalenesynthaseE.HMGCoAthiolase

16.whichisthecorrectsequenceof4reactionsinfattyacidsoxidation?

A.dehydrogenation,redegydrogenation,hydration,thiolysis

B.thiolysis,dehydrogenation,redegydrogenation,hydration

C.dehydrogenation,hydration,redegydrogenation,thiolysis

D.hydration,dehydrogenation,thiolysis,redegydrogenation

E.dehydrogenation,thiolysis,redegydrogenation,hydration

17.whichisthemajorformthattransportsendogenousTAGsfromthelivertothetissues?

A.HDLB.LDLC.VLDLD.CME.IDL

18.whichlipoproteincontainsapoB100mostly?

A.HDLB.LDLC.VLDLD.CME.CMremnants

19.whichlipoproteincontainsapoB48mostly?

A.HDLB.LDLC.VLDLD.CME.IDL

20.whichenzyme‘sactivatorisapoCⅡ?

A.LPLB.LCATC.ACATD.HLE.CETP

21.thenetresultoftheoxidationof1molpalmiticacid（16C）willbe（）molATP?

A.129B.96C.165D.182E.106

22.whichisthemajorformthatparticipatesinthereversecholesteroltransport?

A.IDLB.HDLC.LDLD.VLDLE.CM

23.whichistherate–limitingenzymeintheTAGdegradation?

A.HSLB.LPLC.DAGlipaseD.HLE.MAGlipase

24.whichhormonecanacceleratefatmobilization?

A.epinephrineB.glucagonsC.TSHD.ACTHE.allabove

25.whichisanti-lipolytichormone?

A.epinephrineB.glucagonsC.TSHD.ACTHE.prostaglandinE2

26.whichisessentialfattyacid?

A.stearicacidB.oleicacidC.linoleicacidD.palmiticacidE.oxaloaceticacid

27.whichisthepathwaythatacetyl-CoAistransportedfromthemitochondriaintothecytosoltoallowFAsynthesistooccur?

A.TACcycleB.malate-asparateshuttleC.glucosepyruvatecycle

D.citratepyruvatecycleE.α-glycerophosphateshuttle

28.whichisthekeyenzymeinβ-OxidationofFattyAcids?

（）

A.carnitineacyltransferaseⅠB.carnitineacyltransferaseⅡC.acyl-CoAsynthetase

D.carnitine-acylcaritinetranslocaseE.acetyl-CoAcarboxylase

29.thelackof（）meansthatketonebodiesaresynthesizedexckusivelyintheliverandmustbeusedelsewhere.

A.HMGCoAsynthaseB.succinylCoAtranssulfuraseC.HMGCoAreductase

D.acetoacetyl-CoAthiolaseE.HMGCoAthiolase

30.whichagentisaninhibitorofelectrontransportatComplexⅢ?

A.rotenoneB.antimycinAC.piericidinAD.amobarbitalE.DNP

31.whichagentisnotaninhibitorofelectrontransportatComplexⅣ?

A.carbonmonoxideB.azideC.sulfuretedhydrogenD.amobarbitalE.cyanide

32.whichisnottheenergy-richcompound?

A.CPB.ATPC.PEPD.1,3-bisphoglycerateE.2,3-bisphoglycerate

33.thesequenceofcytochromeinrespiratorychainis:

A.c----c1----b----aa3----O2B.c1----c----b----aa3----O2C.b----c1----c----aa3----O2

D.b----c----c1----aa3----O2E.c----b----c1----aa3----O2

34.Whichofthefollowingstateisnitrogenequilibrium?

A.advancedcancerpatientB.pregnantwomenC.patientrecoveringfromillnessD.peoplesufferformlong-timehungerE.normaladult

35.Whichofthefollowingstatethatnutritionsufficicentinfantin?

A.nitrogenbalanceB.positivenitrogenbalanceC.netativenitrotgenbalanceD.nitrogenequilibriumE.noneoftheabove

36.Whichofthefollowingstateispositivenitrogenbalance?

A.advancedcancerB.pregnantwomenC.peoplesufferfromfeverD.peoplesufferformlong-timehungerE.normaladult

37.Whichofthefollowingisnotonecarbonunit?

CH3;CH2;CO2;CH;CHO

38.WhichofthefollowingisnotproducedbyTyr?

norepinephrine;epinephrine;dopamine;Phe;melanin

39.Whichofthefollowingisthemaindeaminationstyleinmuscle?

Transamination;ornithinecycle;L-glutamateoxidationdeamination;purinenucleotidecycle;γ-glutamylcycle

40.Whichofthefollowingisthestorageandtransportationstyleofammonia?

Glu;Tyr;GSH;Asn;Gln

41.Whichofthefollowingisthemainoutletofammoniainmammalian?

infiltratetointestinaltract;synthesisofGln;synthesisofureainliver;synthesisofaminoacidagain;excreteoutofthebodyinkidney

42.Whichofthefollowingaminoacidcannotproduceonecarbonunit?

Serine;Valine;Tryptophan;Histidine;Glycine

43.Whichofthefollowingamminoacidstakepartinthesynthesisofcreatine?

Glycine,mehionine,arginine;Methionine,ornithine,citrulline;Glycine,methionine,citrulline;Glycine,arginine,ornithine;

Ornithine,citrulline,arginine

44.Whichofthefollowingisthecarrierofonecarbonunit?

biotin;SAM;FH4;FH2;folicacid

45.Whichofthefollowingisketogenicaminoacidonly?

Glycine;Leucine;Threonine;Isoleucine;Tyrosine

46.Whichofthefollowingarethenitrogensourceofurea?

carbomoylphosphateandaspartate;

carbomoylphosphateandornithine;

α-aminogroupandγ-aminogroupofornithine;

α-aminogroupofcitrullineandα-aminogroupofarginine;

γ-aminogroupofornithineandglycine

47.WhichofthefollowingaminoacidcanproducePAPS?

taurine;methionine;cysteine;homocysteine;glutamate

48.Whichofthefollowingisthemaindeaminationstyleinthebody?

oxidationdeamination;reductiondeamination;directdeamination;transamination;uniondeamination

49.Whichofthefollowingistheprocessthattransportammoniafrommuscletoliver?

TACcycle;ornithinecycle;alanine-glucosecycle;methioninecycle;γ-glutamylcycle

50.Whichofthefollowingvitaminthatthecoenzymeofaminoaciddecarboxylasecontain?

C;B2;B12;B6;B1

51.WhichofthefollowingisthedirectdonorofCH3?

N5-CH3-FH4;SAM;N5,N10-CH2-FH4;N5,N10=CH-FH4;FAD

52.Whichofthefollowingisketogenicandglucogenicaminoacid?

Ala;Phe;His;Pro;Leu

53.Whichofthefollowingisthemainsourceofammoniainkidney?

uniondeaminationofaminoacid;hydrolysisofGln;hydrolysisofurea;nonoxidativedeaminationofaminoaicd;oxidationofamine

54.Inthesynthesisofurea,oneNcomefromNH3,whichofthefollowingaminoacidprovideanotherNforurea?

Pro;Asp;Glu;Phe;Lys

55.Whichofthefollowingisfirstsynthesizedintheprocessofdenovosynthesisofpurinenucleotide?

GMP;AMP;IMP;ATP;GTP

56.Whichofthefollowingistheendproductofpurinenucleotidecatabolicmetabolism?

urea;creatine;creatinine;uricacid;β-alanine

57.Whichofthefollowingsubstancedirectlylinknucleotidesynthesisandglucosemetabolism?

glucose;glucose-6-phosphate;glucose-1-phosphate;glucose-1,6-diphosphate;ribose-5-phosphate

58.Whichofthefollowingisnotthedirectmaterialofdenovesynthesisofpurinenucleotide?

glycine;aspartate;glutamate;CO2;onecarbonunit

59.WhichofthefollowingmaterialcouldprovideC4andC5forpurinering?

alanine;glycine;glutamate;aspartate;glutamine

60.WhichofthefollowingprovideonlyoneCatomforpurinesynthesis?

CO2;glutamine;glycine;aspartate;formicacid

61.WhichofthefollowingprovidetwoNatomsforpyrimidinering?

glutamineandammonia;glutamineandglutamate

glutamineandcarbomoylphosphate;aspartateandcarbomoylphosphate;aspartateandglutamate

62.Whichofthefollowingisthecommonmaterialforthesynthesisofpyrimidineandpurinenucleotide?

fumarate;glutamine;formicacid;asparagine;glycine

63.Whichofthefollowingaminoacidtotallyparticipateinthesynthesisofpurinenucleotide?

glycine;aspartate;glutamate;glutamine;asparagines

64.WhichofthefollowingprovideC2forpurinering?

N5-CH3FH4;N10-CHO-FH4;N5，N10=CH-FH4;N5，N10-CH2-FH4;CO2

65.Whichofthefollowingistheenergysourceofbrainforlong-termstarvationpatient?

glucose;aminoacid;glycerol;acetonebody;glucogen

66.Whichofthefollowingisnotcorrectaboutchemicalmodificationofkeyenzyme?

theenzymehavetwostyle:

activeandinactive;theac