乙肝表面抗体阳性核心抗体阳性Hepatitis B surface antibody is positive core antibody is positive.docx
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乙肝表面抗体阳性核心抗体阳性Hepatitis B surface antibody is positive core antibody is positive.docx
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乙肝表面抗体阳性核心抗体阳性HepatitisBsurfaceantibodyispositivecoreantibodyispositive
乙肝表面抗体阳性、核心抗体阳性(HepatitisBsurfaceantibodyispositive,coreantibodyispositive)
HepatitisBsurfaceantibodypositive,hepatitisBcoreantibodypositive
HepatitisBsurfaceantibodyisaprotectiveantibodyofhumanbody,whichcanprotectthebodyfromHBVinfection.HepatitisBcoreantibodypositiveisinfectionorpreviousinfectionmarker.Thesetwosimultaneouspositive,indicatingthatthebodywasoriginallyinfectedwithhepatitisB,isinrecoveryorhasrecovered.
IshepatitisBantibodypositivetobevaccinated?
WhethertoneedtofighthepatitisBvaccinehasthefollowingtwokindsofcircumstances:
1,ifyouarethroughhepatitisBvaccinetoobtainhepatitisBantibody,itisrecommendedthateverythreeyearsyoustrengthentheinjectionofahepatitisBvaccine.SincetheproductionofantibodybyhepatitisBvaccine,theantibodyleveldecreaseswithtime.Mostofourscholarssuggestthatitisbettertostrengthentheinjectiononcethreeyearsafterimmunization.Nomatterhowlongapart,aslongasthesurfaceantibodytiterin10internationalunitsmorethan/ml,indicatingthatthebodyhasimmunitytohepatitisBvirus(variationhepatitisBinvalid).Conversely,ifthehepatitisBsurfaceantibodytiterisbelowthisvalue,theinjectionshouldbeenhanced.
2,ifthehepatitisBsurfaceantibodyisnotobtainedbyinjectionofhepatitisBvaccine,butbecauseofinfectionwithhepatitisBvirusobtained,atthistimedonotneedtoinjecthepatitisBvaccine.ThehepatitisBimmuneantibodyobtainedbyhepatitisBinfectionhasarelativelylongduration.
HepatitisBsurfaceantibodyispositive,canbeeffectiveagainsthepatitisBvirusinvasion,therebyprotectingthebodyfromhepatitisBvirusinfection.ThepreviousgenerationisgenerallybelievedthattheinjectionofhepatitisBvaccineantibody3-5andsustainable,ifoftencontactwithhepatitisBpatientsifantibodyoffsetfaster,inrecentyears,clinicalevidenceofhepatitisBvaccine,hepatitisBsurfaceantibodypositivestimulationofantibodytiterreachedmorethan10,mostcanplayaprotectiverolein8-10,andoftenwithhepatitisBpatientscontactpersonalthoughantibodyoffsetfaster,butbecausethetraceofhepatitisBvirusstimulation,thebodymayalsoproduceantibodies.IfthehepatitisBsurfaceantibodypositive,generallydonothavetoworryaboutthedailylifeofinfection,suggestthat3-5check,inordertoobservetheexistenceanddegreeofantibodies,andantibodyinweaktimelytoensurethecontinuationofhepatitisBvaccine,antibodytiter,andeffectiveagainsthepatitisBvirus,bettermaintenanceofhumanhealth.
HepatitisBsurfaceantibodyappearsweakpositive,mayhavebeeninfectedwithhepatitisBvirus,hasbeenrestoredtohealth.OrinoculationofhepatitisBvaccinemayalsoleadtothisphenomenon,indicatingresistancealready.ThehepatitisBsurfaceantibodyisweakpositive,generallyisnotcontagious,butthehepatitisBantibodytiterwillgraduallydeclinealongwiththetime,sogenerallystrengthensinjectiononceevery4-5years.It'sbettertochecktwo,halfatiterbelow10micrograms,andeverylitershouldbestrengthened.
ThecommonlyusedmethodofinjectinghepatitisBvaccineis"0,1andJuneinjection",thatis,thesecondneedleisinjected1monthsafterthefirstinjection,andthethirdneedleisinjected6monthsafterthefirstneedle.AccordingtothehepatitisBvaccinespecificinstructions,eachsubcutaneousinjectionof5-10micrograms.Seventhmonths,hepatitisBshouldbetestedfiveitems,theeffectofvaccination.IfthehepatitisBsurfaceantibodyispositive,thatiseffective,orelsetoplay.HepatitisBsurfaceantibodyisaprotectiveantibodythatcanprotectthebodyagainsthepatitisBvirus,anditspresenceisthemostimportantindicatoroftheeffectivenessofhepatitisBvaccineinjection.
(1)ifthehepatitisBsurfaceantibodypositiveantibodytiteris>10,showedthattheprotectiveantibodyisenough,cantosomeextentinthepreventionofhepatitisBvirusattacks,withoutinjectionofhepatitisBvaccinetostrengthentheneedle,aftercheckregularly.
(2)ifthesurfaceantibodyofhepatitisBisweakpositive,thatis,thetiterofantibodyis4-10,thenahepatitisBvaccineshouldbeinoculatedtostrengthentheneedle.
HepatitisBsurfaceantibodyquantitativedetectionofnormalvalueislessthan1010mIU/m1,significantlynegative,thebodyisnotenoughtoresisttheinvasionofhepatitisBvirus,hepatitisBissusceptibletothecrowd,thistimetheneedtofighthepatitisBvaccinebooster,therebyenhancingtheantiHBVeffect;ifmorethan10mIU/m1,caneffectivelyresisttheinfectionofhepatitisB,andnumericalbetter.
HepatitisBsurfaceantibody(HBsAb)reacheditspeakin6-12monthsandgraduallydeclinedthereafter,
Turnnegativein10years(sometimesveryfast).
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TwohalfofhepatitisBisthemostcommonlyusedhepatitisBvirus(HBV)infectiondetectionserummarkerindomestichospitals.Thereareatotalof3pairsofhepatitisBvirusimmunologicalmarkers,namelysurfaceantigen(HBsAg)andsurfaceantibody(antiHBsorHBsAb),eantigen(HBeAg)andeantibody(antiHBeorHBeAb),coreantigen(HBcAg)andcoreantibody(antiHBcorHBcAb).HepatitisBtwohalf,alsoknownashepatitisBfive,anditssignificanceis:
checkwhetherthehepatitisBinfectionandthespecificcircumstancesofinfection,distinguishbigSanyang,smallsanyang.
Becausecoreantigenisnoteasytobemeasuredinblood,atpresentthereagentboxdoesnotpass,sotherearetwohalfofantigenantibody,thisiswhatpeopleoftensay"hepatitisBtwohalfandhalf"inspection,orcalled"hepatitisBfive"inspection.
Beforethe"twohalfandhalf",andlateraddedaHBcAb-Igm(coreantibodyIgm),becamethethree,andnowthereisaPre-S1(hepatitisBvirusS1antigen,S1antigen),"twohalfandhalf"intothe"threehalfandhalf".
HepatitisBtwohalfofeachindexsignificance
1(HBsAg-hepatitisBsurfaceantigen)asasignofthevirushasbeeninfected,doesnotreflectwhetherthevirusreplication,replication,infectiousintensity
2(HBsAb-hepatitisBsurfaceantibody)isthehallmarkofneutralizingantibodies,whetherornotamajormarkerofrecoveryorresistance.HepatitisBvaccination,ifonlythepositive,shouldberegardedasanormalphenomenonafterhepatitisBvaccination;hepatitisBvirusinfectionontheirownaftertheeliminationofhepatitisBvirusimmunitywillalsohavethebodyofhepatitisBsurfaceantibody,thisisagoodphenomenon
3(HBeAg-hepatitisBviruseantigen)isamarkerofviralreplication.Continuedpositiveformorethan3monthshaveaffinity
4(HBeAb-hepatitisBviruseantibody)isastopsignforviralreplication.ViralreplicationdecreasesandinfectivityisweakerthantheHBVviruspattern,butnotentirelywithoutinfection
5(HBcAb-coreantibody)isasignofapersonwhohasbeeninfectedorisinfected.Thecoreantibody,IGM,isamarkerofrecentinfectionorviralreplication.ThecoreantibodyIgGisproducedafterinfectionandhassomerelevanceforassistingthetwohalfofthetest.
Surfaceantigen:
indicatedthatthehepatitisBvirus(HBV)hasbeeninfected,becausethesurfaceantigenisthehepatitisBvirus'sshell,onlythispositiveisnotinfectious.70%-90%surfaceantigenpositivelong-term,suchasnosymptoms,andliverfunctionisnormal,nosymptomsofhepatitisBsurfaceantigencarriers,withouttreatment,donotinterferewiththeworkandstudy,theantigenpositiveinthepopulationofChinaaccountsforabout10%.
Surfaceantibody:
ThisisaprotectiveantibodythatneutralizesthehepatitisBvirus.Clew:
itisakindofgoodphenomenontoobtainimmunityafterinoculationhepatitisBvaccine;second,hepatitisBrecoveryperiodoroncesufferedfromhepatitisBalreadymore,expressedalreadyhadimmunity.
Eantigen:
hepatitisBvirusreplication(reproduction)active,infectiousstronger,anditsclosecontact,thepossibilityofinfectionisgreater.Thisantigen,suchaspersistent,suggestschronichepatitisBviruscarriers.
Eantibody:
theconditionthatexpresseshepatitisBpatientisrelieved,stabilityorinclinetorehabilitation,prognosisisgood,infectivitydecreases,butdonotassurethehepatitisBvirushasdisappearedcompletely.
Thisisnotthecoreantibodyantibodyneutralizingantibody,cannotclearthevirus,andoncewasinthebodytoexistforalongtime,herecoveredsustainablepositive,thepositiveonlyrecentlyinfectedwithhepatitisBvirusorviruscontinuestoreplicate(reproduction),orhadhepatitisBvirusinfection,andcannotdistinguishbetweenpastorcurrentinfectionissick.
9commonpatterns
1-thepastandpresenthavenotbeeninfectedwithHBV.
2+-
(1)previousinfectionfailedtodetectresistanceto-HBs;
(2)recoverystageHBsAgdisappearedandanti-HBsdidnotappear;(3)asymptomaticHBsAgcarriers.
3--++
(1)hadpreviouslybeeninfectedwithHBV;
(2)acuteHBVinfectionrecovered;(3)afewspecimenswerestillinfectious.HBVinfectionhaspassed;thewindowperiodbeforetheemergenceofantiHBs.HBeAgappearedlaterinthelatentperiodofhepatitisB,butdisappearedlaterthantheappearanceofHBsAg,
CloselyrelatedtoHBV-DNA.Itsclinicalsignificanceisasfollows:
(1)itcanbeusedasanauxiliarydiagnosisandprognosticindicatorofacutehepatitisB.TherecoveryofacutehepatitisBusuallydisappearswiththedisappearanceofHBsAg.If3-4monthsaftertheonsetofacutehepatitisB,HBeAgispositivefromYang,anti-HBEappears,whichmeanstheprognosisisgood.Onsetof3-6months,stillH
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- 乙肝表面抗体阳性核心抗体阳性Hepatitis surface antibody is positive core 乙肝 表面 抗体 阳性 核心 Hepatitis
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