IARC致癌物Word文档格式.docx
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IARC致癌物Word文档格式.docx
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inpreparation)
(NB:
Overallevaluationupgradedfrom2Bto1basedonmechanisticandotherrelevantdata)
Beryllium[7440-41-7]andberylliumcompounds(Vol.58;
1993)
N,N-Bis(2-chloroethyl)-2-naphthylamine(Chlornaphazine)[494-03-1](Vol.4,Suppl.7;
Bis(chloromethyl)ether[542-88-1]andchloromethylmethylether[107-30-2](technical-grade)
(Vol.4,Suppl.7;
1,4-Butanedioldimethanesulfonate(Busulphan;
Myleran)[55-98-1](Vol.4,Suppl.7;
Cadmium[7440-43-9]andcadmiumcompounds(Vol.58;
Chlorambucil[305-03-3](Vol.26,Suppl.7;
1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea(Methyl-CCNU;
Semustine)[13909-09-6](Suppl.7;
Chromium[VI](Vol.49;
1990)
Ciclosporin[79217-60-0](Vol.50;
Cyclophosphamide[50-18-0][6055-19-2](Vol.26,Suppl.7;
Diethylstilboestrol[56-53-1](Vol.21,Suppl.7;
Epstein-Barrvirus(Vol.70;
1997)
Erionite[66733-21-9](Vol.42,Suppl.7;
Estrogen-progestogenmenopausaltherapy(combined)(Vol.72,Vol.91;
inpreparation)
Estrogen-progestogenoralcontraceptives(combined)(Vol.72,Vol.91;
Thereisalsoconvincingevidenceinhumansthattheseagentsconferaprotectiveeffectagainstcancerintheendometriumandovary)
Estrogens,nonsteroidal(Suppl.7;
Estrogens,steroidal(Suppl.7;
Estrogentherapy,postmenopausal(Vol.72;
1999)
Ethyleneoxide[75-21-8](Vol.60;
1994)(NB:
Overallevaluationupgradedfrom2Ato1withsupportingevidencefromotherrelevantdata)
Etoposide[33419-42-0]incombinationwithcisplatinandbleomycin(Vol.76;
2000)
Formaldehyde[50-00-0](Vol.88;
2006)
Galliumarsenide[1303-00-0](Vol.86;
[GammaRadiation:
seeX-andGamma(g)-Radiation]
Helicobacterpylori(infectionwith)(Vol.61;
1994)
HepatitisBvirus(chronicinfectionwith)(Vol.59;
HepatitisCvirus(chronicinfectionwith)(Vol.59;
Humanimmunodeficiencyvirustype1(infectionwith)(Vol.67;
1996)
Humanpapillomavirustypes16,18,31,33,35,39,45,51,52,56,58,59and66(Vol.64,Vol.90;
inpreparation)(NB:
TheHPVtypesthathavebeenclassifiedascarcinogenictohumanscandifferbyanorderofmagnitudeinriskforcervicalcancer)
HumanT-celllymphotropicvirustypeI(Vol.67;
Melphalan[148-82-3](Vol.9,Suppl.7;
8-Methoxypsoralen(Methoxsalen)[298-81-7]plusultravioletAradiation(Vol.24,Suppl.7;
MOPPandothercombinedchemotherapyincludingalkylatingagents(Suppl.7;
Mustardgas(Sulfurmustard)[505-60-2](Vol.9,Suppl.7;
2-Naphthylamine[91-59-8](Vol.4,Suppl.7;
Neutrons(Vol.75;
2000)(NB:
Overallevaluationupgradedfrom2Bto1withsupportingevidencefromotherrelevantdata)
Nickelcompounds(Vol.49;
N'
-Nitrosonornicotine(NNN)[16543-55-8]and4-(N-Nitrosomethylamino)-1-(3-pyridyl)-1-butanone(NNK)[64091-91-4](Vol.37,Suppl.7,Vol.89;
[Oestrogen:
seeEstrogen]
Opisthorchisviverrini(infectionwith)(Vol.61;
[Oralcontraceptives,combinedestrogen-progestogen:
seeEstrogen-progestogenoralcontraceptives(combined)]
Oralcontraceptives,sequential(Suppl.7;
Phosphorus-32,asphosphate(Vol.78;
2001)
Plutonium-239anditsdecayproducts(maycontainplutonium-240andotherisotopes),asaerosols(Vol.78;
Radioiodines,short-livedisotopes,includingiodine-131,fromatomicreactoraccidentsandnuclearweaponsdetonation(exposureduringchildhood)(Vol.78;
Radionuclides,a-particle-emitting,internallydeposited(Vol.78;
SpecificradionuclidesforwhichthereissufficientevidenceforcarcinogenicitytohumansarealsolistedindividuallyasGroup1agents)
Radionuclides,b-particle-emitting,internallydeposited(Vol.78;
Radium-224anditsdecayproducts(Vol.78;
Radium-226anditsdecayproducts(Vol.78;
Radium-228anditsdecayproducts(Vol.78;
Radon-222[10043-92-2]anditsdecayproducts(Vol.43,Vol.78;
Schistosomahaematobium(infectionwith)(Vol.61;
Silica[14808-60-7],crystalline(inhaledintheformofquartzorcristobalitefromoccupationalsources)(Vol.68;
Solarradiation(Vol.55;
1992)
Talccontainingasbestiformfibres(Vol.42,Suppl.7;
Tamoxifen[10540-29-1](Vol.66;
1996)(NB:
Thereisalsoconclusiveevidencethattamoxifenreducestheriskofcontralateralbreastcancer)
2,3,7,8-Tetrachlorodibenzo-para-dioxin[1746-01-6](Vol.69;
1997)(NB:
Thiotepa[52-24-4](Vol.50;
Thorium-232anditsdecayproducts,administeredintravenouslyasacolloidaldispersionofthorium-232dioxide(Vol.78;
Treosulfan[299-75-2](Vol.26,Suppl.7;
Vinylchloride[75-01-4](Vol.19,Suppl.7;
X-andGamma(g)-Radiation(Vol.75;
Mixtures
Aflatoxins(naturallyoccurringmixturesof)[1402-68-2](Vol.56,Vol.82;
2002)
Alcoholicbeverages(Vol.44;
1988)
Arecanut(Vol.85;
2004)(NB:
Overallevaluationbasedonhumandata,animaldata,andmechanisticandotherrelevantdata)
Betelquidwithtobacco(Vol.85;
2004)
Betelquidwithouttobacco(Vol.85;
Coal-tarpitches[65996-93-2](Vol.35,Suppl.7;
Coal-tars[8007-45-2](Vol.35,Suppl.7;
HerbalremediescontainingplantspeciesofthegenusAristolochia(Vol.82;
Householdcombustionofcoal,indooremissionsfrom(Vol.95;
Mineraloils,untreatedandmildlytreated(Vol.33,Suppl.7;
Phenacetin,analgesicmixturescontaining(Suppl.7;
Saltedfish(Chinese-style)(Vol.56;
Shale-oils[68308-34-9](Vol.35,Suppl.7;
Soots(Vol.35,Suppl.7;
Tobacco,smokeless(Vol.37,Suppl.7,Vol.89;
Wooddust(Vol.62;
1995)
Exposurecircumstances
Aluminiumproduction(Vol.34,Suppl.7;
Arsenicindrinking-water(Vol.84;
Auramine,manufactureof(Suppl.7;
Bootandshoemanufactureandrepair(Vol.25,Suppl.7;
Chimneysweeping(Vol.92;
Coalgasification(Vol.34,Suppl.7,Vol.92;
Coal-tardistillation(Vol.92;
Cokeproduction(Vol.34,Suppl.7,Vol.92;
Furnitureandcabinetmaking(Vol.25,Suppl.7;
Haematitemining(underground)withexposuretoradon(Vol.1,Suppl.7;
Involuntarysmoking(exposuretosecondhandor'
environmental'
tobaccosmoke)(Vol.83;
Ironandsteelfounding(Vol.34,Suppl.7;
Isopropylalcoholmanufacture(strong-acidprocess)(Suppl.7;
Magenta,manufactureof(Vol.57;
Painter(occupationalexposureasa)(Vol.47;
1989)
Pavingandroofingwithcoal-tarpitch(Vol.92;
Rubberindustry(Vol.28,Suppl.7;
Strong-inorganic-acidmistscontainingsulfuricacid(occupationalexposureto)(Vol.54;
Tobaccosmokingandtobaccosmoke(Vol.83;
Lastupdated:
13December2006
Group2A:
Probablycarcinogenictohumans(68)
Acrylamide[79-06-1](Vol.60;
Overallevaluationupgradedfrom2Bto2Awithsupportingevidencefromotherrelevantdata)
Adriamycin[23214-92-8](Vol.10,Suppl.7;
Androgenic(anabolic)steroids(Suppl.7;
Aristolochicacids(naturallyoccurringmixturesof)(Vol.82;
Azacitidine[320-67-2](Vol.50;
1990)(NB:
Benzidine-baseddyes(Suppl.7;
Bischloroethylnitrosourea(BCNU)[154-93-8](Vol.26,Suppl.7;
1,3-Butadiene[106-99-0](Vol.71;
Captafol[2425-06-1](Vol.53;
1991)(NB:
Chloramphenicol[56-75-7](Vol.50;
α-Chlorinatedtoluenes(benzalchloride[98-87-3],benzotrichloride[98-07-7],benzylchloride[100-44-7])andbenzoylchloride[98-88-4](combinedexposures)(Vol.29,Suppl.7,Vol.71;
1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea(CCNU)[13010-47-4](Vol.26,Suppl.7;
4-Chloro-ortho-toluidine[95-69-2](Vol.77;
Chlorozotocin[54749-90-5](Vol.50;
Overallevaluationupgradedfrom2Bto2Awithsupportingevidencefromo
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