化妆品清洗和消毒培训_精品文档PPT格式课件下载.ppt
- 文档编号:15478359
- 上传时间:2022-11-01
- 格式:PPT
- 页数:63
- 大小:805.50KB
化妆品清洗和消毒培训_精品文档PPT格式课件下载.ppt
《化妆品清洗和消毒培训_精品文档PPT格式课件下载.ppt》由会员分享,可在线阅读,更多相关《化妆品清洗和消毒培训_精品文档PPT格式课件下载.ppt(63页珍藏版)》请在冰豆网上搜索。
DisinfectionPeterJay:
@#@Bioscience,UR&@#@DPSTrumbull,US14-16thNovember2006BackgroundlRecentyearsweaknessesincleaninganddisinfectionhavebeenthemajorcauseofincidents.lRecognisedthatgreateremphasisonadherencetobestpracticeprinciplesisrequired.lOnsitevalidationofproceduresisakeyareathatneedstobeimproved.IncidentLearnings-Disinfection
(1)lWater/DiluteProductResiduesLeftinPlant.PlantNOTdisinfectedpriortouselMANYincidentslDisinfectionprocedureNOTvalidatedlOperatorsINADEQUATELYtrainedlOperatordidNOTfollowdocumenteddisinfectionprocedurelDisinfectionNOTperformedwhenrequiredIncidentLearnings-Disinfection
(2)lDisinfectionprocedureinathirdpartydidNOTfollowanapprovedpractice.lINADEQUATEcontrolofshutdownprocedureslPortableequipmentNOTadequatelycleanedanddisinfectedpriortouse.INCIDENTLEARNING-C&@#@DEnsurewater/productdrainsfromallareasofplantbygooddesignpractice.Ifnondrainableareasareidentified,theyMUSTbemanagedbydisinfectionprocedurespriortouseoftheplantUndrainablepipearrangementUndrainablepumparrangementWater/DiluteProductResiduesLeftinPlantINCIDENTLEARNINGC&@#@DTimeImmediatelypostclean=30bugs/mlGrowthoccurs.24Hourslater=10millionbugs/mlAssumeundrainablepumpholdstwolitresofdiluteproductresidues:
@#@After24hours20,000,000,000bugswillbepresentinthe2litresofwater!
@#@-Wouldyoubathinthis?
@#@-Wouldyoudrinkthis?
@#@-Wouldyoumakeproductwiththis?
@#@Undrainablepipearrangement-LeavingDiluteProductresidues=“BUGFOOD”Water/DiluteProductResiduesLeftinPlantUndrainableCleaningandDisinfectionRulesINCIDENTLEARNINGSEnsureCleaningandDisinfectionprotocolsaredocumentedandoperatorsaretrainedintheprocedures.RegularchecksbylocalhygienistarerequiredtoensurecomplianceWHENWHOHOWMUSTBEDEFINEDANDDOCUMENTEDTRAININGiskeyDISIPLINEINIMPLEMENTATIONisessentialCleaningandDisinfectionDisinfectionlDestructionofmicro-organismsbutNOTusuallybacterialspores.lDisinfectiondoesNOTnecessarilykillallmicro-organismsbutreducesthemtoalevelacceptableforadefinedpurpose,e.g.toalevelwhichisnotharmfuleithertohealthortothequalityofthegoodsbeingprocessed.CleaningandDisinfection-HACCPlCanbehandledasaGMPorasdefinedCCPslPreferredrouteisasCCPslEspeciallywhenstartingonHACCPlConsiderCIPsysteminHACCPstudylConsiderwhereneedmanualinterventionWhyCleanlProcesslPurposetoremoveproductsoilsandresiduestoproducecleanequipmentsurfacesthatwillnottaintthesubsequentproductionofadifferingvariant.lMicrobiologicallPreparationoftheplantsurfacesfordisinfection.Residualproductleftinequipmentcanpreventeffectivedisinfection:
@#@Deactivatesomechemicaldisinfectants.Physicalbarrierpreventingthesuccessfuleliminationofthemicro-organismsbyprotectingthemRemainingproductresidueswillalsoactasafoodsourceforresidentmicro-organisms.Poorcleaningcanincreasetheriskofcontaminationthroughtheformationofdiluteandhencemorehospitableproductresidues(sublethalpreservativelevels).WhyDisinfectlWedoNOToperatesterileprocesseslThereforesomemicro-organismsWILLenterthemanufacturingplantlDisinfectionstrategiesarerequiredtopreventthebuildupofcontaminationintheplanttoalevelthatwillresultinoutofspecificationproductlDisinfectionshouldreducethemicrobialloadonasurfacetoalevelthatwillNOTbecapableofsurvivingorgrowinginfinishedproductDisinfectionlEquipmentmustbecleantobeeffectivelydisinfected.lEquipmentmustbedraineddrytoremaindisinfectedforanyperiodoftime.lDisinfectiononlyprotectsequipmentforalimitedtime.HowtoDisinfectlTwooptions:
@#@lHeatlChemicalsThermalDisinfectionlRecommendedmethodofdisinfectionlTemperaturesof70degreesfor10minuteswilleffectivelydisinfectplant(coldestpartofplantmustreachtheseconditions)lTargettemperatureMUSTbeattainedatthecoldestpartoftheplant/circuitbeingdisinfected.l10minutecontacttimeshallNOTbestarteduntilallpartsofthecircuithavereachedthistemperature.lItmaytakeinexcessof15minutesforallpartsofplantcircuit(varieswithconfiguration/equipment)toreachthistemperature.lValidationtime/temperatureisCRITICALlLowertemperaturesandcontacttimeswillNOTdeliverdisinfection.ThermalDisinfectionlHeatmoreeffectivethanchemicaldisinfectionindestroyingbiofilmslEquipmentmustbeabletowithstandhightemperaturesandbeengineeredcorrectlytoavoidimplosionoftanks.lSteam:
@#@RarelyusedoutsideUSPlantsnotdesigned(seals/instrumentsetc.)tohandlesteamlOnlyeffectiveagainstnonsporeformingmicro-organismslProtectionagainstscaldingrequiredlThermalDisinfectionGuidelinesfortheManufactureofHPCLiquids.ThisdocumentisavailableontheGlobalHygieneSecurityGroupwebsiteunderTechnicalDocuments.ChemicalDisinfectionlReli
- 配套讲稿:
如PPT文件的首页显示word图标,表示该PPT已包含配套word讲稿。双击word图标可打开word文档。
- 特殊限制:
部分文档作品中含有的国旗、国徽等图片,仅作为作品整体效果示例展示,禁止商用。设计者仅对作品中独创性部分享有著作权。
- 关 键 词:
- 化妆品 清洗 消毒 培训 精品 文档